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The democratization of the oncogene.


ABSTRACT: The identification of novel, oncogenic gene rearrangements in inflammatory myofibroblastic tumor demonstrates the potential of next-generation sequencing (NGS) platforms for the detection of therapeutically relevant oncogenes across multiple tumor types, but raises significant questions relating to the investigation of targeted therapies in this new era of widespread NGS testing.

SUBMITTER: Le AT 

PROVIDER: S-EPMC4123669 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature

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The democratization of the oncogene.

Le Anh T AT   Doebele Robert C RC  

Cancer discovery 20140801 8


The identification of novel, oncogenic gene rearrangements in inflammatory myofibroblastic tumor demonstrates the potential of next-generation sequencing (NGS) platforms for the detection of therapeutically relevant oncogenes across multiple tumor types, but raises significant questions relating to the investigation of targeted therapies in this new era of widespread NGS testing. ...[more]

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