Ontology highlight
ABSTRACT:
SUBMITTER: Suzuki S
PROVIDER: S-EPMC4123905 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Suzuki Shuji S Kakuta Masanori M Ishida Takashi T Akiyama Yutaka Y
PloS one 20140806 8
DNA sequences are translated into protein coding sequences and then further assigned to protein families in metagenomic analyses, because of the need for sensitivity. However, huge amounts of sequence data create the problem that even general homology search analyses using BLASTX become difficult in terms of computational cost. We designed a new homology search algorithm that finds seed sequences based on the suffix arrays of a query and a database, and have implemented it as GHOSTX. GHOSTX achi ...[more]