Ontology highlight
ABSTRACT:
SUBMITTER: Zeidan AM
PROVIDER: S-EPMC4124605 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Blood reviews 20130727 5
After being a neglected and poorly-understood disorder for many years, there has been a recent explosion of data regarding the complex pathogenesis of myelodysplastic syndromes (MDS). On the therapeutic front, the approval of azacitidine, decitabine, and lenalidomide in the last decade was a major breakthrough. Nonetheless, the responses to these agents are limited and most patients progress within 2 years. Allogeneic stem cell transplantation remains the only potentially curative therapy, but i ...[more]