Ontology highlight
ABSTRACT:
SUBMITTER: Wang K
PROVIDER: S-EPMC4126647 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wang Kai K Phillips Charles A CA Rogers Gary L GL Barrenas Fredrik F Benson Mikael M Langston Michael A MA
International journal of computational biology and drug design 20140528 2-3
Differential expression has been a standard tool for analysing case-control transcriptomic data since the advent of microarray technology. It has proved invaluable in characterising the molecular mechanisms of disease. Nevertheless, the expression profile of a gene across samples can be perturbed in ways that leave the expression level unaltered, while a biological effect is nonetheless present. This paper describes and analyses differential Shannon entropy and differential coefficient of variat ...[more]