Ontology highlight
ABSTRACT:
SUBMITTER: Takai M
PROVIDER: S-EPMC4127950 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Takai Masaaki M Terai Yoshito Y Kawaguchi Hiroshi H Ashihara Keisuke K Fujiwara Satoe S Tanaka Tomohito T Tsunetoh Satoshi S Tanaka Yoshimichi Y Sasaki Hiroshi H Kanemura Masanori M Tanabe Akiko A Ohmichi Masahide M
Journal of ovarian research 20140727
<h4>Objectives</h4>The epithelial-mesenchymal-transition (EMT) is an important step in the invasion and metastasis of cancer. A critical molecular feature of this process is the downregulation of the E-cadherin expression, which is primarily controlled by Snail-related zinc-finger transcription factors. The aim of this study was to evaluate the prognostic impact of the expression of EMT-related proteins (E-cadherin and Snail) in patients with ovarian cancer.<h4>Methods</h4>An immunohistochemical ...[more]