Dataset Information

AIDS-related mycoses: the way forward.

ABSTRACT: The contribution of fungal infections to the morbidity and mortality of HIV-infected individuals is largely unrecognized. A recent meeting highlighted several priorities that need to be urgently addressed, including improved epidemiological surveillance, increased availability of existing diagnostics and drugs, more training in the field of medical mycology, and better funding for research and provision of treatment, particularly in developing countries.

SUBMITTER: Brown GD

PROVIDER: S-EPMC4129449 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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Publications

AIDS-related mycoses: the way forward.

Brown Gordon D GD Meintjes Graeme G Kolls Jay K JK Gray Clive C Horsnell William W Achan Beatrice B Alber Gottfried G Aloisi Maria M Armstrong-James Darius D Beale Mathew M Bicanic Tihana T Black John J Bohjanen Paul P Botes Angela A Boulware David R DR Brown Gordon G Bunjun Rubina R Carr William W Casadevall Arturo A Chang Christina C Chivero Ernest E Corcoran Craig C Cross Anna A Dawood Halima H Day Jeremy J De Bernardis Flavia F De Jager Veronique V De Repentigny Louis L Denning David D Eschke Maria M Finkelman Malcolm M Govender Nelesh N Gow Neil N Graham Lisa L Gryschek Ronaldo R Hammond-Aryee Kenneth K Harrison Tom T Heard Neil N Hill Melanie M Hoving J Claire JC Janoff Edward E Jarvis Joseph J Kayuni Sekeleghe S King Karin K Kolls Jay J Kullberg Bart-Jan BJ Lalloo David G DG Letang Emilio E Levitz Stuart S Limper Andrew A Longley Nicky N Machiridza Tendai Rodney TR Mahabeer Yesholata Y Martinsons Neil N Meiring Susan S Meya David D Miller Robert R Molloy Sile S Morris Lynn L Mukaremera Liliane L Musubire Abdu K AK Muzoora Conrad C Nair Amy A Nakiwala Kimbowa Justine J Netea Mihai M Nielsen Kirsten K O'hern Jennifer J Okurut Samuel S Parker Arifa A Patterson Tom T Pennap Grace G Perfect John J Prinsloo Chrisna C Rhein Joshua J Rolfes Melissa A MA Samuel Catherine C Schutz Charlotte C Scriven James J Sebolai Olihile M OM Sojane Katlego K Sriruttan Charlotte C Stead David D Steyn Annica A Thawer Narjis K NK Thienemann Friedrich F Von Hohenberg Maximilian M Vreulink Jo-marie JM Wessels Jeannette J Wood Kathryn K Yang Yun-liang YL

Trends in microbiology 20140301 3

The contribution of fungal infections to the morbidity and mortality of HIV-infected individuals is largely unrecognized. A recent meeting highlighted several priorities that need to be urgently addressed, including improved epidemiological surveillance, increased availability of existing diagnostics and drugs, more training in the field of medical mycology, and better funding for research and provision of treatment, particularly in developing countries. ...[more]

PMID: 24581941

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Project description:BACKGROUND:With India preparing for the next decennial Census in 2021, we compared the disability estimates and data collection methodology between the Census 2011 and the most recent population-level survey for India and its states, to highlight the issues to be addressed to improve robustness of the disability estimates in the upcoming Census. METHODS:Data from the Census 2011 and from two complementary nationally representative household surveys that covered all Indian states with the same methodology and survey instruments-the District-Level Household Survey-4 (DLHS-4, 2012-2013) and the Annual Health Surveys (AHS three rounds, 2010-11, 2011-12 and 2012-13) were used. Data from DLHS-4 and AHS 2012-13 round were pooled to generate estimates for the year 2012-13. Data collection methodology between the sources was compared, including the review of definitions of each type of disability. The overall, mental, visual, hearing, speech, and movement disability rate (DR) per 100,000 population were compared between the sources for India and for each state, and the percent difference in the respective rates was calculated. We explored the reliability of these estimates comparing yearly data from the AHS for three successive rounds. RESULTS:Survey data were collected through proxy reporting, however, it is not entirely clear whether the data were proxy- or self-reported or a mix of both in the Census. The overall DR was 25.1% higher in the Census (2,242; 95% CI 2,241-2,243) than the survey (1,791; 95% CI 1,786-1,797) per 100,000 population, with the state-level difference ranging from -64% in Tamil Nadu to 107% in Sikkim state. Despite both sources using nearly similar definitions for overall disability and disability by type, the difference in DR was 125.5%, 54.2%, -25.7%, -19.7%, and 21.9% for hearing, speech, mental, movement, and visual DR, respectively. At the state-level, the difference in disability-specific estimates ranged from -84% to 450%. The extent of variations in the disability-specific estimates in AHS successive rounds ranged from -25% to 929% at the state-level. CONCLUSIONS:There is momentum globally towards building disability measurement that is consistent with the data required for monitoring of the Sustainable Development Goals to ensure robust estimation of disability. The current estimates from the Census and surveys seem much lower than would be expected at the population level. We make recommendations that India needs to take serious note of in order to improve the validity and reliability of India's disability estimates.

Dataset Information

AIDS-related mycoses: the way forward.

Publications

AIDS-related mycoses: the way forward.

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