Ontology highlight
ABSTRACT:
SUBMITTER: Di Fruscia P
PROVIDER: S-EPMC4130903 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Bioorganic & medicinal chemistry letters 20140620 16
Neurotensin (NT) is an endogenous tridecapeptide found in the central nervous system (CNS) and in peripheral tissues. Neurotensin exerts a wide range of physiological effects and it has been found to play a critical role in a number of human diseases, such as schizophrenia, Parkinson's disease and drug addiction. The discovery of small-molecule non-peptide neurotensin receptor (NTSR) modulators would represent an important breakthrough as such compounds could be used as pharmacological tools, to ...[more]