Ontology highlight
ABSTRACT:
SUBMITTER: Goldie BJ
PROVIDER: S-EPMC4132720 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Goldie Belinda J BJ Dun Matthew D MD Lin Minjie M Smith Nathan D ND Verrills Nicole M NM Dayas Christopher V CV Cairns Murray J MJ
Nucleic acids research 20140722 14
Rapid input-restricted change in gene expression is an important aspect of synaptic plasticity requiring complex mechanisms of post-transcriptional mRNA trafficking and regulation. Small non-coding miRNA are uniquely poised to support these functions by providing a nucleic-acid-based specificity component for universal-sequence-dependent RNA binding complexes. We investigated the subcellular distribution of these molecules in resting and potassium chloride depolarized human neuroblasts, and foun ...[more]