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Health care worker exposures to the antibacterial agent triclosan.


ABSTRACT: We sought to quantify absorption of triclosan, a potential endocrine disruptor, in health care workers with occupational exposure to soap containing this chemical.A cross-sectional convenience sample of two groups of 38 health care workers at separate inpatient medical centers: hospital 1 uses 0.3% triclosan soap in all patient care areas; hospital 2 does not use triclosan-containing products. Additional exposure to triclosan-containing personal care products was assessed through a structured questionnaire. Urine triclosan was quantified and the occupational contribution estimated through regression modeling.Occupational exposure accounted for an incremental triclosan burden of 206 ng/mL (P = 0.02), while triclosan-containing toothpaste use was associated with 146 ng/mL higher levels (P < 0.001).Use of triclosan-containing antibacterial soaps in health care settings represents a substantial and potentially biologically relevant source of occupational triclosan exposure.

SUBMITTER: MacIsaac JK 

PROVIDER: S-EPMC4133120 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature

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Health care worker exposures to the antibacterial agent triclosan.

MacIsaac Julia K JK   Gerona Roy R RR   Blanc Paul D PD   Apatira Latifat L   Friesen Matthew W MW   Coppolino Michael M   Janssen Sarah S  

Journal of occupational and environmental medicine 20140801 8


<h4>Objective</h4>We sought to quantify absorption of triclosan, a potential endocrine disruptor, in health care workers with occupational exposure to soap containing this chemical.<h4>Methods</h4>A cross-sectional convenience sample of two groups of 38 health care workers at separate inpatient medical centers: hospital 1 uses 0.3% triclosan soap in all patient care areas; hospital 2 does not use triclosan-containing products. Additional exposure to triclosan-containing personal care products wa  ...[more]

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