Ontology highlight
ABSTRACT:
SUBMITTER: Micek MA
PROVIDER: S-EPMC4133577 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
The Journal of infectious diseases 20140304 4
Acquisition of nevirapine (NVP)-resistant human immunodeficiency virus type 1 (HIV-1) by breast-feeding infants after receipt of single-dose NVP to prevent mother-to-child transmission is not well defined. A prospective observational study of 307 infants evaluated the rate of breast milk transmission of NVP-resistant HIV and the concentrations of mutants over time. NVP resistance was detected in 9 of 24 infants (37.5%; 95% confidence interval, 18.8%-59.4%) infected via breast milk. Eight had a p ...[more]