Ontology highlight
ABSTRACT:
SUBMITTER: Liu M
PROVIDER: S-EPMC4134679 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Liu Minji M Wang Xiaoyan X Peng Ya Y Shen Shourong S Li Guiyuan G
BMC molecular biology 20140716
<h4>Background</h4>As a novel candidate metastasis suppressor gene, Nasopharyngeal carcinoma-associated gene 6 (NGX6) is involved in cellular growth, cell cycle progression and tumor angiogenesis. Previous studies have shown that NGX6 gene is down-regulated in colorectal cancer (CRC). However, little is known about its transcriptional regulation.<h4>Results</h4>We defined the minimal promoter of NGX6 gene in a 186-bp region (from-86 to +100) through mutation construct methods and luciferase assa ...[more]