MiR-3960 binding sites with mRNA of human genes.
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ABSTRACT:
SUBMITTER: Ivashchenko A
PROVIDER: S-EPMC4135290 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
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MiR-3960 binding sites with mRNA of human genes.
Ivashchenko Anatoly A Berillo Olga O Pyrkova Anna A Niyazova Raigul R Atambayeva Shara S
Bioinformation 20140722 7
The importance of miRNA in cellular regulation is gaining momentum. Therefore, it is of interest to study miRNA in human genes. Hence, the humanmRNA sequences (12,175) were searched for miRNA binding sites and 2,563predicted sites were found. We observed that the miR-3960 has more than 1000mRNA binding sites with high affinity (with ΔG/ΔGm values greater than or equal to 90%) for 375genes. The miR-3960 has 565 binding sites in the 5'UTRs and 515 sites in theCDS of mRNAs. Nucleotide sequences of ...[more]
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