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The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to antituberculosis treatment.


ABSTRACT: We evaluated the use of the molecular bacterial load (MBL) assay, for measuring viable Mycobacterium tuberculosis in sputum, in comparison with solid agar and liquid culture. The MBL assay provides early information on the rate of decline in bacterial load and has technical advantages over culture in either form.

SUBMITTER: Honeyborne I 

PROVIDER: S-EPMC4136187 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature

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The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to antituberculosis treatment.

Honeyborne Isobella I   Mtafya Bariki B   Phillips Patrick P J PP   Hoelscher Michael M   Ntinginya Elias N EN   Kohlenberg Anke A   Rachow Andrea A   Rojas-Ponce Gabriel G   McHugh Timothy D TD   Heinrich Norbert N  

Journal of clinical microbiology 20140528 8


We evaluated the use of the molecular bacterial load (MBL) assay, for measuring viable Mycobacterium tuberculosis in sputum, in comparison with solid agar and liquid culture. The MBL assay provides early information on the rate of decline in bacterial load and has technical advantages over culture in either form. ...[more]

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