Ontology highlight
ABSTRACT:
SUBMITTER: Colella S
PROVIDER: S-EPMC4136479 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Head & neck 20081001 10
<h4>Background</h4>Metastases are the primary cause of cancer treatment failure and death, yet metastatic mechanisms remain incompletely understood.<h4>Methods</h4>We studied the molecular basis of head and neck cancer metastasis by transcriptionally profiling 70 samples from 27 patients-matching normal adjacent tissue, primary tumor, and cervical lymph node metastases.<h4>Results</h4>We identified tumor-associated expression signatures common to both primary tumors and metastases. Use of matchi ...[more]