Unknown

Dataset Information

0

Changes in nucleosome occupancy occur in a chromosome specific manner.


ABSTRACT: In the eukaryotic nucleus, DNA is packaged into chromatin. The fundamental subunit of chromatin is the nucleosome, DNA is wrapped 1.6 times around a histone octamer core. Nuclear processes in eukaryotes are impacted by whether regulatory DNA is occupied by nucleosomes. We used microarrays to measure nucleosome occupancy in human cells post Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation at hundreds of immunity-related loci. The detailed analysis of these technologies can be found in recent publications from our lab (Druliner et al., 2013; Sexton et al., 2014). We found that nucleosome redistributions displayed chromosome specific nucleosome occupancy. This resource can be used to map nucleosome distributions in a variety of biological contexts.

SUBMITTER: Sexton BS 

PROVIDER: S-EPMC4138544 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC3117357 | biostudies-literature
| S-EPMC5393060 | biostudies-literature
| S-EPMC4250828 | biostudies-literature
| S-EPMC6126743 | biostudies-literature
| S-EPMC3209338 | biostudies-literature
| S-EPMC4035975 | biostudies-literature
| S-EPMC2808325 | biostudies-literature
| S-EPMC2515632 | biostudies-literature
| S-EPMC3458375 | biostudies-literature
| S-EPMC10766401 | biostudies-literature