Ontology highlight
ABSTRACT:
SUBMITTER: Eisenegger C
PROVIDER: S-EPMC4138746 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Eisenegger Christoph C Naef Michael M Linssen Anke A Clark Luke L Gandamaneni Praveen K PK Müller Ulrich U Robbins Trevor W TW
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20140409 10
Influential neurocomputational models emphasize dopamine (DA) as an electrophysiological and neurochemical correlate of reinforcement learning. However, evidence of a specific causal role of DA receptors in learning has been less forthcoming, especially in humans. Here we combine, in a between-subjects design, administration of a high dose of the selective DA D2/3-receptor antagonist sulpiride with genetic analysis of the DA D2 receptor in a behavioral study of reinforcement learning in a sample ...[more]