Ontology highlight
ABSTRACT:
SUBMITTER: Yang SH
PROVIDER: S-EPMC4139087 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Yang Shih-Hung SH Wang Seu-Mei SM Syu Jhih-Pu JP Chen Ying Y Wang Sheng-De SD Peng Yu-Sen YS Kuo Meng-Fai MF Kung Hsiu-Ni HN
BioMed research international 20140805
<h4>Background</h4>Glioma is the most malignant tumor of the central nervous system. Efforts on the development of new chemotherapy are mandatory. Andrographolide (AND), a diterpenoid lactone isolated from the Andrographis paniculata, has been shown to have antitumor activities in several types of cancer cells. Whether AND can exert its antitumor activity in glioblastoma cells remains unknown. This study examined the anticancer effects of AND, both in vitro and in vivo.<h4>Methods</h4>Cell apopt ...[more]