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Hemorrhage rates and risk factors in the natural history course of brain arteriovenous malformations.


ABSTRACT: Brain arteriovenous malformations (AVMs) are abnormal connections of arteries and veins, resulting in arteriovenous shunting of blood. Primary medical therapy is lacking; treatment options include surgery, radiosurgery, and embolization, often in combination. Judicious selection of AVM patients for treatment requires balancing risk of treatment complications against the risk of hemorrhage in the natural history course. This review focuses on the epidemiology, hemorrhage risk, and factors influencing risk of hemorrhage in the untreated natural course associated with sporadic brain AVM.

SUBMITTER: Rutledge WC 

PROVIDER: S-EPMC4139097 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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Hemorrhage rates and risk factors in the natural history course of brain arteriovenous malformations.

Rutledge W Caleb WC   Ko Nerissa U NU   Lawton Michael T MT   Kim Helen H  

Translational stroke research 20140615 5


Brain arteriovenous malformations (AVMs) are abnormal connections of arteries and veins, resulting in arteriovenous shunting of blood. Primary medical therapy is lacking; treatment options include surgery, radiosurgery, and embolization, often in combination. Judicious selection of AVM patients for treatment requires balancing risk of treatment complications against the risk of hemorrhage in the natural history course. This review focuses on the epidemiology, hemorrhage risk, and factors influen  ...[more]

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