Ontology highlight
ABSTRACT:
SUBMITTER: Srimani JK
PROVIDER: S-EPMC4139379 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Srimani Jaydeep K JK Yao Guang G Neu John J Tanouchi Yu Y Lee Tae Jun TJ You Lingchong L
PloS one 20140820 8
Many cellular decision processes, including proliferation, differentiation, and phenotypic switching, are controlled by bistable signaling networks. In response to transient or intermediate input signals, these networks allocate a population fraction to each of two distinct states (e.g. OFF and ON). While extensive studies have been carried out to analyze various bistable networks, they are primarily focused on responses of bistable networks to sustained input signals. In this work, we investiga ...[more]