Ontology highlight
ABSTRACT:
SUBMITTER: Mitchell DA
PROVIDER: S-EPMC4140262 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Mitchell David A DA Hamel Laura D LD Reddy Krishna D KD Farh Lynn L Rettew Logan M LM Sanchez Phillip R PR Deschenes Robert J RJ
The Journal of biological chemistry 20140508 26
Early onset intellectual disabilities result in significant societal and economic costs and affect 1-3% of the population. The underlying genetic determinants are beginning to emerge and are interpreted in the context of years of work characterizing postsynaptic receptor and signaling functions of learning and memory. DNA sequence analysis of intellectual disability patients has revealed greater than 80 loci on the X-chromosome that are potentially linked to disease. One of the loci is zDHHC9, a ...[more]