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Predictors of future health-related quality of life in survivors of adolescent cancer.


ABSTRACT: The purpose of this study was to identify characteristics associated with health-related quality of life (HRQOL) among long-term survivors of adolescent cancer enrolled in the Childhood Cancer Survivor Study. Thirty percent of survivors reported poor physical and/or mental HRQOL. Race/ethnicity, education, and head/neck disfigurement were significantly associated with poor mental HRQOL, while sex, age, household income, obesity, alkylating agents, pelvic radiation, head/neck or limb disfigurement, and walking with a limp were associated with poor physical HRQOL. Identification of high-risk adolescent cancer patients may facilitate timely intervention to attempt to minimize the impact of cancer and treatment on subsequent quality of life.

SUBMITTER: Nolan VG 

PROVIDER: S-EPMC4141009 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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Predictors of future health-related quality of life in survivors of adolescent cancer.

Nolan Vikki G VG   Krull Kevin R KR   Gurney James G JG   Leisenring Wendy W   Robison Leslie L LL   Ness Kirsten K KK  

Pediatric blood & cancer 20140324 10


The purpose of this study was to identify characteristics associated with health-related quality of life (HRQOL) among long-term survivors of adolescent cancer enrolled in the Childhood Cancer Survivor Study. Thirty percent of survivors reported poor physical and/or mental HRQOL. Race/ethnicity, education, and head/neck disfigurement were significantly associated with poor mental HRQOL, while sex, age, household income, obesity, alkylating agents, pelvic radiation, head/neck or limb disfiguremen  ...[more]

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