Ontology highlight
ABSTRACT:
SUBMITTER: Wei P
PROVIDER: S-EPMC4141757 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wei Peng P Xu Lida L Li Cheng-Dong CD Sun Fu-De FD Chen Long L Tan Tianwei T Luo Shi-Zhong SZ
PloS one 20140822 8
The DAP12-NKG2C activating immunoreceptor complex is one of the multisubunit transmembrane protein complexes in which ligand-binding receptor chains assemble with dimeric signal-transducing modules through non-covalent associations in their transmembrane (TM) domains. In this work, both coarse grained and atomistic molecular dynamic simulation methods were applied to investigate the self-assembly dynamics of the transmembrane domains of the DAP12-NKG2C activating immunoreceptor complex. Through ...[more]