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Autoimmune disease prevalence in a multiple sclerosis cohort in Argentina.

ABSTRACT: Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentinean MS patients. Results. There were no significant differences in autoimmune disease prevalence in MS patients with respect to controls. The presence of one or more autoimmune disorders did not increase risk of MS (OR 0.85, 95%?CI 0.6-1.3). Discussion. Our results indicate absence of increased comorbid autoimmune disease prevalence in MS patients, as well as of increased risk of MS in patients suffering from other autoimmune disorders.

SUBMITTER: Farez MF

PROVIDER: S-EPMC4142150 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Autoimmune disease prevalence in a multiple sclerosis cohort in Argentina.

Farez Mauricio F MF Balbuena Aguirre María E ME Varela Francisco F Köhler Alejandro A AA Correale Jorge J

Multiple sclerosis international 20140806

Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentinean MS patients. Results. There were no significant differences in autoimmune disease prevalence in MS patients with respect to controls. The presence of one or more autoimmune disorders did not incre ...[more]

PMID: 25170425

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