Ontology highlight
ABSTRACT:
SUBMITTER: Wang R
PROVIDER: S-EPMC4142315 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wang Rui R Zhang Jun J Jiang Weiru W Ma Yanyun Y Li Wenshuai W Jin Bohan B Hu Heping H Wang Jiucun J Liu Yi Y Liu Jie J
TheScientificWorldJournal 20140807
<h4>Background</h4>Single-nucleotide polymorphisms in microRNAs play important roles in oncogenesis and cancer development. Objective. We aim to explore whether miR-646 rs6513497 is associated with the risk of hepatocellular carcinoma.<h4>Methods</h4>Total 997 HCC patients and 993 cancer-free controls were enrolled in this study. Genotyping was performed using MassARRAY method.<h4>Results</h4>Compared with the T allele of rs6513497, the G allele was associated with a significantly decreased risk ...[more]