Estimation of treatment policies based on functional predictors.
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ABSTRACT:
SUBMITTER: McKeague IW
PROVIDER: S-EPMC4142446 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Publications
Estimation of treatment policies based on functional predictors.
Statistica Sinica 20140701 3
Biosignatures such as brain scans, mass spectrometry, or gene expression profiles might one day be used to guide treatment selection and improve outcomes. This article develops a way of estimating optimal treatment policies based on data from randomized clinical trials by interpreting patient biosignatures as functional predictors. A flexible functional regression model is used to represent the treatment effect and construct the estimated policy. The effectiveness of the estimated policy is asse ...[more]
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2019-08-20 | GSE110146 | GEO