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Rethinking vector immunology: the role of environmental temperature in shaping resistance.


ABSTRACT: Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. As temperatures in the field can vary greatly from the ambient temperature in the laboratory, it will be essential to take temperature into account when studying vector immunology.

SUBMITTER: Murdock CC 

PROVIDER: S-EPMC4142813 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Rethinking vector immunology: the role of environmental temperature in shaping resistance.

Murdock Courtney C CC   Paaijmans Krijn P KP   Cox-Foster Diana D   Read Andrew F AF   Thomas Matthew B MB  

Nature reviews. Microbiology 20121113 12


Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. As temperatures in the field can vary greatly from the ambient temperature in the laboratory, it will be essenti  ...[more]

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