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ABSTRACT:
SUBMITTER: Simmler C
PROVIDER: S-EPMC4143180 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Simmler Charlotte C Nikolić Dejan D Lankin David C DC Yu Yang Y Friesen J Brent JB van Breemen Richard B RB Lecomte Alicia A Le Quémener Céline C Audo Grégoire G Pauli Guido F GF
Journal of natural products 20140731 8
Licorice botanicals are produced from the roots of Glycyrrhiza species (Fabaceae), encompassing metabolites of both plant and rhizobial origin. The composition in both primary and secondary metabolites (1°/2°Ms) reflects the physiologic state of the plant at harvest. Interestingly, the relative abundance of 1°Ms vs 2°Ms in licorice extracts remains undetermined. A centrifugal partition chromatography (CPC) method was developed to purify liquiritin derivatives that represent major bioactive 2°Ms ...[more]