Ontology highlight
ABSTRACT:
SUBMITTER: Lee JW
PROVIDER: S-EPMC4143249 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Lee Jeong Woo JW Choi Seong-O SO Felner Eric I EI Prausnitz Mark R MR
Small (Weinheim an der Bergstrasse, Germany) 20110104 4
The clinical impact of biotechnology has been constrained by the limitations of traditional hypodermic injection of biopharmaceuticals. Microneedle patches have been proposed as a minimally invasive alternative. In this study, the translation of a dissolving microneedle patch designed for simple, painless self-administration of biopharmacetucials that generates no sharp biohazardous waste is assessed. To study the pharmacokinetics and safety of this approach, human growth hormone (hGH) was encap ...[more]