Ontology highlight
ABSTRACT:
SUBMITTER: Fan R
PROVIDER: S-EPMC4143762 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Fan Ruixue R Huang Chien-Hsun CH Hu Inchi I Wang Haitian H Zheng Tian T Lo Shaw-Hwa SH
BMC proceedings 20140617 Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo
It is believed that almost all common diseases are the consequence of complex interactions between genetic markers and environmental factors. However, few such interactions have been documented to date. Conventional statistical methods for detecting gene and environmental interactions are often based on the linear regression model, which assumes a linear interaction effect. In this study, we propose a nonparametric partition-based approach that is able to capture complex interaction patterns. We ...[more]