Prospects and pitfalls of personalizing therapies for sarcomas: from children, adolescents, and young adults to the elderly.

ABSTRACT: Sarcomas are a heterogeneous class of tumors that affect all ages, from children, adolescents, and young adults to the elderly. Within this panoply of tumor subtypes lies the opportunity to bring to bear a vision of personalized medicine in which the fast-paced evolution from the "one gene, one test, one drug" approach to a comprehensive "panomic," multiplex, multianalyte method coupled with advances in bioinformatics platforms can unravel the biology of this disease. The increasingly enlarging repertoire of novel agents provides innumerable prospects in precision medicine. Personalized therapy covers the entire spectrum of cancer care, from risk factor assessment through prevention, risk reduction, therapy, follow-up after therapy, and survivorship care. Challenges remain in implementing

SUBMITTER: Subbiah V 

PROVIDER: S-EPMC4144039 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature