Ontology highlight
ABSTRACT:
SUBMITTER: Huo Y
PROVIDER: S-EPMC4148055 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Journal of computational biology : a journal of computational molecular cell biology 20140804 9
Metabolic flux analysis (MFA), a key technology in bioinformatics, is an effective way of analyzing the entire metabolic system by measuring fluxes. Many existing MFA approaches are based on differential equations, which are complicated to be solved mathematically. So MFA requires some simple approaches to investigate metabolism further. In this article, we applied continuous-time Markov chain to MFA, called MMFA approach, and transformed the MFA problem into a set of quadratic equations by anal ...[more]