Ontology highlight
ABSTRACT:
SUBMITTER: Naegeli A
PROVIDER: S-EPMC4148877 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Naegeli Andreas A Michaud Gaëlle G Schubert Mario M Lin Chia-Wei CW Lizak Christian C Darbre Tamis T Reymond Jean-Louis JL Aebi Markus M
The Journal of biological chemistry 20140624 35
N-Linked protein glycosylation is a very common post-translational modification that can be found in all kingdoms of life. The classical, highly conserved pathway entails the assembly of a lipid-linked oligosaccharide and its transfer to an asparagine residue in the sequon NX(S/T) of a secreted protein by the integral membrane protein oligosaccharyltransferase. A few species in the class of γ-proteobacteria encode a cytoplasmic N-glycosylation system mediated by a soluble N-glycosyltransferase ( ...[more]