Ontology highlight
ABSTRACT:
SUBMITTER: Lomsadze A
PROVIDER: S-EPMC4150757 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Lomsadze Alexandre A Burns Paul D PD Borodovsky Mark M
Nucleic acids research 20140702 15
We present a new approach to automatic training of a eukaryotic ab initio gene finding algorithm. With the advent of Next-Generation Sequencing, automatic training has become paramount, allowing genome annotation pipelines to keep pace with the speed of genome sequencing. Earlier we developed GeneMark-ES, currently the only gene finding algorithm for eukaryotic genomes that performs automatic training in unsupervised ab initio mode. The new algorithm, GeneMark-ET augments GeneMark-ES with a nove ...[more]