Ontology highlight
ABSTRACT:
SUBMITTER: Hasnain S
PROVIDER: S-EPMC4152264 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
PloS one 20140902 9
A new coarse-grained model of the E. coli cytoplasm is developed by describing the proteins of the cytoplasm as flexible units consisting of one or more spheres that follow Brownian dynamics (BD), with hydrodynamic interactions (HI) accounted for by a mean-field approach. Extensive BD simulations were performed to calculate the diffusion coefficients of three different proteins in the cellular environment. The results are in close agreement with experimental or previously simulated values, where ...[more]