Ontology highlight
ABSTRACT:
SUBMITTER: Nella AA
PROVIDER: S-EPMC4154103 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Nella A A AA Lodish M B MB Fox E E Balis F M FM Quezado M M MM Whitcomb P O PO Derdak J J Kebebew E E Widemann B C BC Stratakis C A CA
The Journal of clinical endocrinology and metabolism 20140311 9
<h4>Context</h4>Ectopic Cushing syndrome due to ACTH secretion from metastatic medullary thyroid cancer (MTC) is associated with significant morbidity and mortality.<h4>Objective</h4>The aim of the study was to describe the first case of Cushing syndrome associated with MTC in a pediatric patient and the successful reversal of Cushing syndrome with tyrosine kinase inhibitor (vandetanib) therapy.<h4>Patient and methods</h4>A 17-year-old Brazilian adolescent presented with metastatic MTC and assoc ...[more]