Ontology highlight
ABSTRACT:
SUBMITTER: Wojtowicz-Krawiec A
PROVIDER: S-EPMC4154517 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wojtowicz-Krawiec Anna A Sokolowska Iwona I Smorawinska Maria M Chojnacka-Puchta Luiza L Mikiewicz Diana D Lukasiewicz Natalia N Marciniak-Rusek Alina A Wolinowska Renata R Bierczynska-Krzysik Anna A Porebska Anna Joanna AJ Kuthan-Styczen Jolanta J Gurba Lidia L Borowicz Piotr P Mazurkiewicz Anna A Plucienniczak Grazyna G Plucienniczak Andrzej A
Microbial cell factories 20140827 1
<h4>Background</h4>Numerous bacterial human growth hormone (hGH) expression methods under conventional fermentation and induction conditions have been described. Despite significant progress made in this area over the past several years, production of recombinant hGH by using cellular expression systems still requires further optimization. Fusion of the ubiquitin (Ub) tag to the hGH protein allowed to increase of the overall efficiency of the biosynthesis and improve the protein stability. Ub is ...[more]