Ontology highlight
ABSTRACT:
SUBMITTER: Dunne E
PROVIDER: S-EPMC4155514 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Dunne Eimear E Spring Christopher M CM Reheman Adili A Jin Wuxun W Berndt Michael C MC Newman Debra K DK Newman Peter J PJ Ni Heyu H Kenny Dermot D
Arteriosclerosis, thrombosis, and vascular biology 20120426 7
<h4>Objective</h4>Thrombosis occurs at sites of vascular injury when platelets adhere to subendothelial matrix proteins and to each other. Platelets express many surface receptor proteins, the function of several of these remains poorly characterized. Cadherin 6 is expressed on the platelet surface and contains an arginine-glycine-aspartic acid motif, suggesting that it might have a supportive role in thrombus formation. The aim of this study was to characterize the role of cadherin 6 in platele ...[more]