Erythrocyte very long-chain saturated fatty acids associated with lower risk of incident sudden cardiac arrest.

ABSTRACT: Prior studies suggest that circulating n-3 and trans-fatty acids influence the risk of sudden cardiac arrest (SCA). Yet, while other fatty acids also differ in their membrane properties and biological activities which may influence SCA, little is known about the associations of other circulating fatty acids with SCA. The aim of this study was to investigate the associations of 17 erythrocyte membrane fatty acids with SCA risk. We used data from a population-based case-control study of SCA in the greater Seattle, Washington, area. Cases, aged 25-74 years, were out-of-hospital SCA patients, attended by paramedics (n=265). Controls, matched to cases by age, sex and calendar year, were randomly identified from the community (n=415). All participants were free of prior clinically-diagnosed hear

SUBMITTER: Lemaitre RN 

PROVIDER: S-EPMC4156887 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature