Increased susceptibility of beta7-integrin-deficient neonatal mice in the early stage of Cryptosporidium parvum infection.
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ABSTRACT:
SUBMITTER: Mancassola R
PROVIDER: S-EPMC415699 | biostudies-literature | 2004 Jun
REPOSITORIES: biostudies-literature
Publications
Increased susceptibility of beta7-integrin-deficient neonatal mice in the early stage of Cryptosporidium parvum infection.
Mancassola Roselyne R Lacroix-Lamandé Sonia S Barrier Mathieu M Naciri Muriel M Salmon Henri H Laurent Fabrice F
Infection and immunity 20040601 6
Numerous inflammatory cells are recruited in response to Cryptosporidium parvum infection. These cells include interferon gamma-producing T lymphocytes, which are of major importance for the resolution of infection. Here, we show that beta7 integrin is not essential for the control of infection in mice but that beta7-deficient neonatal mice are more susceptible during the early stages of infection. ...[more]
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