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Chronic heroin dependence leading to adrenal insufficiency.

ABSTRACT: Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of opioids.

SUBMITTER: Das G

PROVIDER: S-EPMC4158160 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Chronic heroin dependence leading to adrenal insufficiency.

Das Gautam G

Case reports in endocrinology 20140820

Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of ...[more]

PMID: 25221675

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A Rare Presentation of Possible Disseminated Histoplasmosis with Adrenal Insufficiency Leading to Adrenal Crisis in an Immunocompetent Adult: A Case Report.

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Clinical characteristics of adrenal crisis in adult population with and without predisposing chronic adrenal insufficiency: a retrospective cohort study.

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Characterization of patients with adrenal insufficiency and frequent adrenal crises.

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