Ontology highlight
ABSTRACT:
SUBMITTER: Jiang X
PROVIDER: S-EPMC4158574 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Jiang Xupin X Guo Xiaowei X Xu Xue X Teng Miao M Huang Chong C Zhang Dongxia D Zhang Qiong Q Zhang Jiaping J Huang Yuesheng Y
Scientific reports 20140909
Keratinocyte migration is an early event in the wound healing process. Although we previously found that CD9 downregulation is required for the keratinocyte migration during wound repair, the mechanism of how CD9 expression is regulated remains unclear. Here, we observed the effect of hypoxia (2% O2) on CD9 expression and keratinocyte migration. CD9 expression was downregulated and keratinocyte migration was increased under hypoxic conditions. In addition, CD9 overexpression reversed hypoxia-ind ...[more]