Ontology highlight
ABSTRACT:
SUBMITTER: Chinello C
PROVIDER: S-EPMC4159280 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Chinello Clizia C Cazzaniga Marta M De Sio Gabriele G Smith Andrew James AJ Gianazza Erica E Grasso Angelica A Rocco Francesco F Signorini Stefano S Grasso Marco M Bosari Silvano S Zoppis Italo I Dakna Mohammed M van der Burgt Yuri E M YE Mauri Giancarlo G Magni Fulvio F
PloS one 20140909 9
Renal Cell Carcinoma (RCC) is typically asymptomatic and surgery usually increases patient's lifespan only for early stage tumours. Moreover, solid renal masses cannot be confidently differentiated from RCC. Therefore, markers to distinguish malignant kidney tumours and for their detection are needed. Two different peptide signatures were obtained by a MALDI-TOF profiling approach based on urine pre-purification by C8 magnetic beads. One cluster of 12 signals could differentiate malignant tumour ...[more]