Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microscale assembly directed by liquid-based template.

ABSTRACT: A liquid surface established by standing waves is used as a dynamically reconfigurable template to assemble microscale materials into ordered, symmetric structures in a scalable and parallel manner. The broad applicability of this technology is illustrated by assembling diverse materials from soft matter, rigid bodies, individual cells, cell spheroids and cell-seeded microcarrier beads.

SUBMITTER: Chen P

PROVIDER: S-EPMC4159433 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

Microscale assembly directed by liquid-based template.

Chen Pu P Luo Zhengyuan Z Güven Sinan S Tasoglu Savas S Ganesan Adarsh Venkataraman AV Weng Andrew A Demirci Utkan U

Advanced materials (Deerfield Beach, Fla.) 20140623 34

A liquid surface established by standing waves is used as a dynamically reconfigurable template to assemble microscale materials into ordered, symmetric structures in a scalable and parallel manner. The broad applicability of this technology is illustrated by assembling diverse materials from soft matter, rigid bodies, individual cells, cell spheroids and cell-seeded microcarrier beads. ...[more]

PMID: 24956442

Similar Datasets

Highly conductive tissue-like hydrogel interface through template-directed assembly.

Project description:Over the past decade, conductive hydrogels have received great attention as tissue-interfacing electrodes due to their soft and tissue-like mechanical properties. However, a trade-off between robust tissue-like mechanical properties and good electrical properties has prevented the fabrication of a tough, highly conductive hydrogel and limited its use in bioelectronics. Here, we report a synthetic method for the realization of highly conductive and mechanically tough hydrogels with tissue-like modulus. We employed a template-directed assembly method, enabling the arrangement of a disorder-free, highly-conductive nanofibrous conductive network inside a highly stretchable, hydrated network. The resultant hydrogel exhibits ideal electrical and mechanical properties as a tissue-interfacing material. Furthermore, it can provide tough adhesion (800 J/m2) with diverse dynamic wet tissue after chemical activation. This hydrogel enables suture-free and adhesive-free, high-performance hydrogel bioelectronics. We successfully demonstrated ultra-low voltage neuromodulation and high-quality epicardial electrocardiogram (ECG) signal recording based on in vivo animal models. This template-directed assembly method provides a platform for hydrogel interfaces for various bioelectronic applications.

| S-EPMC10113367 | biostudies-literature

Template-directed self-assembly of dynamic covalent capsules with polar interiors.

Project description:Chiral polyimine molecular capsules with polar interiors have been prepared through template covalent dynamic self-assembly. An aryl-extended tetraaldehyde calix[4]pyrrole scaffold was condensed with suitable diamines as linkers using templates for efficient self-assembly. The capsular complexes were characterized in solution, gas phase and the solid-state. Unprecedented transfer of asymmetry was observed from a chiral diamine linker to the resulting supramolecular capsular assembly.

| S-EPMC5853267 | biostudies-literature

Ligand-Directed Template Assembly for the Construction of Gigantic Molybdenum Blue Wheels.

Project description:Template-mediated synthesis is a powerful approach to build a variety of functional materials and complex supramolecular systems. However, the systematic study of how templates structurally evolve from basic building blocks, and then affect the templated self-assembly, is critical to understanding and utilizing the underlying mechanism, to work towards designed assembly. Here we describe the templated self-assembly of a series of gigantic Mo Blue (MB) clusters 1-4 using l-ornithine as a structure-directing ligand. We show that by using l-ornithine as a structure director, we can form new template?host assemblies. Based on the structural relationship between encapsulated templates of {Mo8 } (1), {Mo17 } (2) and {Mo36 } (4), a pathway of the structural evolution of templates is proposed. This provides insight into how gigantic Mo Blue cluster rings form and could lead to full control over the designed assembly of gigantic Mo-blue rings.

| S-EPMC6771582 | biostudies-literature

"Size-selectivity" in the template-directed assembly of dinuclear triple-stranded helicates.

Project description:The self-assembly of supramolecular structures depends on a subtle interplay of a series of different control mechanisms. The geometric as well as electronic complementarity of the molecular building blocks is crucial for the specific formation of defined supramolecular species. In addition, secondary effects, like templating, also have an important function. The templating ability of different cations in the formation of triple-stranded helicate-type complexes from alkyl-bridged di(8-hydroxyquinoline) ligands is investigated by introduction of alkyl chains of different length as ligand spacers. Hereby a "size-selectivity" between the cations and the dinuclear helicate-type complexes [(ligand)(3)M(2)] is observed. Large cations support the formation of big dinuclear complexes, whereas small cations are able to template the formation of small complexes.

| S-EPMC122685 | biostudies-literature

A prebiotic template-directed peptide synthesis based on amyloids.

Project description:The prebiotic replication of information-coding molecules is a central problem concerning life's origins. Here, we report that amyloids composed of short peptides can direct the sequence-selective, regioselective and stereoselective condensation of amino acids. The addition of activated DL-arginine and DL-phenylalanine to the peptide RFRFR-NH2 in the presence of the complementary template peptide Ac-FEFEFEFE-NH2 yields the isotactic product FRFRFRFR-NH2, 1 of 64 possible triple addition products, under conditions in which the absence of template yields only single and double additions of mixed stereochemistry. The templating mechanism appears to be general in that a different amyloid formed by (Orn)V(Orn)V(Orn)V(Orn)V-NH2 and Ac-VDVDVDVDV-NH2 is regioselective and stereoselective for N-terminal, L-amino-acid addition while the ornithine-valine peptide alone yields predominantly sidechain condensation products with little stereoselectivity. Furthermore, the templating reaction is stable over a wide range of pH (5.6-8.6), salt concentration (0-4 M NaCl), and temperature (25-90 °C), making the amyloid an attractive model for a prebiotic peptide replicating system.

| S-EPMC5770463 | biostudies-literature

Understanding Interactions Driving the Template-Directed Self-Assembly of Colloidal Nanoparticles at Surfaces.

Project description:Controlled deposition of colloidal nanoparticles using self-assembly is a promising technique for, for example, manufacturing of miniaturized electronics, and it bridges the gap between top-down and bottom-up methods. However, selecting materials and geometry of the target surface for optimal deposition results presents a significant challenge. Here, we describe a predictive framework based on the Derjaguin-Landau-Verwey-Overbeek theory that allows rational design of colloidal nanoparticle deposition setups. The framework is demonstrated for a model system consisting of gold nanoparticles stabilized by trisodium citrate that are directed toward prefabricated sub-100 nm features on a silicon substrate. Experimental results for the model system are presented in conjunction with theoretical analysis to assess its reliability. It is shown that three-dimensional, nickel-coated structures are well suited for attracting gold nanoparticles and that optimization of the feature geometry based on the proposed framework leads to a systematic improvement in the number of successfully deposited particles.

| S-EPMC7050997 | biostudies-literature

Directed self-assembly of liquid crystalline blue-phases into ideal single-crystals.

Project description:Chiral nematic liquid crystals are known to form blue phases-liquid states of matter that exhibit ordered cubic arrangements of topological defects. Blue-phase specimens, however, are generally polycrystalline, consisting of randomly oriented domains that limit their performance in applications. A strategy that relies on nano-patterned substrates is presented here for preparation of stable, macroscopic single-crystal blue-phase materials. Different template designs are conceived to exert control over different planes of the blue-phase lattice orientation with respect to the underlying substrate. Experiments are then used to demonstrate that it is indeed possible to create stable single-crystal blue-phase domains with the desired orientation over large regions. These results provide a potential avenue to fully exploit the electro-optical properties of blue phases, which have been hindered by the existence of grain boundaries.

| S-EPMC5481765 | biostudies-literature

Dynamic-template-directed multiscale assembly for large-area coating of highly-aligned conjugated polymer thin films.

Project description:Solution processable semiconducting polymers have been under intense investigations due to their diverse applications from printed electronics to biomedical devices. However, controlling the macromolecular assembly across length scales during solution coating remains a key challenge, largely due to the disparity in timescales of polymer assembly and high-throughput printing/coating. Herein we propose the concept of dynamic templating to expedite polymer nucleation and the ensuing assembly process, inspired by biomineralization templates capable of surface reconfiguration. Molecular dynamic simulations reveal that surface reconfigurability is key to promoting template-polymer interactions, thereby lowering polymer nucleation barrier. Employing ionic-liquid-based dynamic template during meniscus-guided coating results in highly aligned, highly crystalline donor-acceptor polymer thin films over large area (>1?cm2) and promoted charge transport along both the polymer backbone and the ?-? stacking direction in field-effect transistors. We further demonstrate that the charge transport anisotropy can be reversed by tuning the degree of polymer backbone alignment.

| S-EPMC5511351 | biostudies-literature

Synthesis of a Peptidoyl RNA Hairpin via a Combination of Solid-Phase and Template-Directed Chain Assembly.

Project description:Peptidoyl RNAs are the products of ribosome-free, single-nucleotide translation. They contain a peptide in the backbone of the oligoribonucleotide and are interesting from a synthetic and a bioorganic point of view. A synthesis of a stabilized version of peptidoyl RNA, with an amide bond between the C-terminus of a peptide and a 3'-amino-2',3'-dideoxynucleoside in the RNA chain was developed. The preferred synthetic route used an N-Teoc-protected aminonucleoside support and involved a solution-phase coupling of the amino-terminal oligonucleotide to a dipeptido dinucleotide. Exploratory UV-melting and NMR analysis of the hairpin 5'-UUGGCGAAAGCdC-LeuLeu-AA-3' indicated that the peptide-linked RNA segments do not fold in a cooperative fashion. The synthetic access to doubly RNA-linked peptides on a scale sufficient for structural biology opens the door to the exploration of their structural and biochemical properties.

| S-EPMC9542650 | biostudies-literature

A facile dual-template-directed successive assembly approach to hollow multi-shell mesoporous metal-organic framework particles.

Project description:Hollow multi-shell mesoporous metal-organic framework (MOF) particles with accessible compartmentalization environments, plentiful heterogeneous interfaces, and abundant framework diversity are expected to hold great potential for catalysis, energy conversion, and biotechnology. However, their synthetic methodology has not yet been established. In this work, a facile dual-template-directed successive assembly approach has been developed for the preparation of monodisperse hollow multi-shell mesoporous MOF (UiO-66-NH2) particles through one-step selective etching of successively grown multi-layer MOFs with alternating two types of mesostructured layers. This strategy enables the preparation of hollow multi-shell mesoporous UiO-66-NH2 nanostructures with controllable shell numbers, accessible mesochannels, large pore volume, tunable shell thickness and chamber sizes. The methodology relies on creating multiple alternating layers of two different mesostructured MOFs via dual-template-directed successive assembly and their difference in framework stability upon chemical etching. Benefiting from the highly accessible Lewis acidic sites and the accumulation of reactants within the multi-compartment architecture, the resultant hollow multi-shell mesoporous UiO-66-NH2 particles exhibit enhanced catalytic activity for CO2 cycloaddition reaction. The dual-template-directed successive assembly strategy paves the way toward the rational construction of elaborate hierarchical MOF nanoarchitectures with specific physical and chemical features for different applications.

| S-EPMC10698178 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data