Ontology highlight
ABSTRACT:
SUBMITTER: Jung CH
PROVIDER: S-EPMC4160579 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Jung Chang Hee CH Jang Jung Eun JE Park Joong-Yeol JY
Diabetes & metabolism journal 20140801 4
Type 2 diabetes mellitus (T2DM) is a complex endocrine and metabolic disorder, and a major public health problem that is rapidly increasing in prevalence. Although a wide range of pharmacotherapies for glycemic control is now available, management of T2DM remains complex and challenging. The kidneys contribute immensely to glucose homeostasis by reabsorbing glucose from the glomerular filtrate. Sodium-glucose cotransporter 2 (SGLT2) inhibitors, a new class of antidiabetic agents that inhibit glu ...[more]