Ontology highlight
ABSTRACT:
SUBMITTER: Chao FA
PROVIDER: S-EPMC4161213 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Journal of magnetic resonance (San Diego, Calif. : 1997) 20140502
We present an enhanced version of the FLAMEnGO (Fuzzy Logic Assignment of Methyl Group) software, a structure-based method to assign methyl group resonances in large proteins. FLAMEnGO utilizes a fuzzy logic algorithm coupled with Monte Carlo sampling to obtain a probability-based assignment of the methyl group resonances. As an input, FLAMEnGO requires either the protein X-ray structure or an NMR structural ensemble including data such as methyl-methyl NOESY, paramagnetic relaxation enhancement ...[more]