Bio-inspired cryo-ink preserves red blood cell phenotype and function during nanoliter vitrification.
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ABSTRACT:
SUBMITTER: El Assal R
PROVIDER: S-EPMC4161503 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
Bio-inspired cryo-ink preserves red blood cell phenotype and function during nanoliter vitrification.
El Assal Rami R Guven Sinan S Gurkan Umut Atakan UA Gozen Irep I Shafiee Hadi H Dalbeyler Sedef S Abdalla Noor N Thomas Gawain G Fuld Wendy W Illigens Ben M W BM Estanislau Jessica J Khoory Joseph J Kaufman Richard R Zylberberg Claudia C Lindeman Neal N Wen Qi Q Ghiran Ionita I Demirci Utkan U
Advanced materials (Deerfield Beach, Fla.) 20140722 33
Current red-blood-cell cryopreservation methods utilize bulk volumes, causing cryo-injury of cells, which results in irreversible disruption of cell morphology, mechanics, and function. An innovative approach to preserve human red-blood-cell morphology, mechanics, and function following vitrification in nanoliter volumes is developed using a novel cryo-ink integrated with a bioprinting approach. ...[more]
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2023-09-20 | GSE227091 | GEO