Epigenetics of lung cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Langevin SM
PROVIDER: S-EPMC4162853 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Publications
Epigenetics of lung cancer.
Langevin Scott M SM Kratzke Robert A RA Kelsey Karl T KT
Translational research : the journal of laboratory and clinical medicine 20140312 1
Lung cancer is the leading cause of cancer-related mortality in the United States. Epigenetic alterations, including DNA methylation, histone modifications, and noncoding RNA expression, have been reported widely in the literature to play a major role in the genesis of lung cancer. The goal of this review is to summarize the common epigenetic changes associated with lung cancer to give some clarity to its etiology, and to provide an overview of the potential translational applications of these c ...[more]
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