Ontology highlight
ABSTRACT:
SUBMITTER: Mattis J
PROVIDER: S-EPMC4165888 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Mattis Joanna J Tye Kay M KM Ferenczi Emily A EA Ramakrishnan Charu C O'Shea Daniel J DJ Prakash Rohit R Gunaydin Lisa A LA Hyun Minsuk M Fenno Lief E LE Gradinaru Viviana V Yizhar Ofer O Deisseroth Karl K
Nature methods 20111218 2
Diverse optogenetic tools have allowed versatile control over neural activity. Many depolarizing and hyperpolarizing tools have now been developed in multiple laboratories and tested across different preparations, presenting opportunities but also making it difficult to draw direct comparisons. This challenge has been compounded by the dependence of performance on parameters such as vector, promoter, expression time, illumination, cell type and many other variables. As a result, it has become in ...[more]