Ontology highlight
ABSTRACT:
SUBMITTER: Hao H
PROVIDER: S-EPMC4167819 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Hao Hailing H Li Ying Y Tzatzalos Evangeline E Gilbert Jordana J Zala Dhara D Bhaumik Mantu M Cai Li L
Developmental biology 20140619 1
Precise control of lineage-specific gene expression in the neural stem/progenitor cells is crucial for generation of the diversity of neuronal and glial cell types in the central nervous system (CNS). The mechanism underlying such gene regulation, however, is not fully elucidated. Here, we report that a 377 bp evolutionarily conserved DNA fragment (CR5), located approximately 32 kbp upstream of Olig2 transcription start site, acts as a cis-regulator for gene expression in the development of the ...[more]