Ontology highlight
ABSTRACT:
SUBMITTER: Takada H
PROVIDER: S-EPMC4169011 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Takada Hitomi H Saito Yutaka Y Mituyama Toutai T Wei Zong Z Yoshihara Eiji E Jacinto Sandra S Downes Michael M Evans Ronald M RM Kida Yasuyuki S YS
Epigenetics 20140710 9
Although DNA modification is adaptive to extrinsic demands, little is known about epigenetic alterations associated with adipose differentiation and reprogramming. We systematically characterized the global trends of our methylome and transcriptome data with reported PPAR(γ) cistrome data. Our analysis revealed that DNA methylation was altered between induced pluripotent stem cells (iPSCs) and adipose derived stem cells (ADSCs). Surprisingly, DNA methylation was not obviously changed in differen ...[more]